Density Ellipses: display a bivariate normal density contour. All Topics JMP Basics Graphical Displays and Summaries Probabilities and Distributions. This resulted in a method to statistically differentiate between the dissolution processes of the capsules in different media. Fit Line (new in JMP 9): Display a simple linear regression line in each scatterplot. Doing so will produce the same results for the Type III sums-of-squares as R, when you use the car package and appropriate contrasts. The dissolution processes were further characterized using a non-linear regression fit of a power law function to the data for each capsule. You can override that default by unclicking that option under the red triangle by 'Model Specification' in the 'Fit Model' dialog box. The time specific linear contrasts showed the largest sum of square values (SS) occurred at 180 min (SS=0.268) for the simulated SIF (pH 6.8) versus SGF (pH 1.2) comparison (DF=166, MSE=3.92 x 10(-3)). The model provided us with statistically powerful criteria to identify significant differences in capsule dissolution across time and to quantify capsule-to-capsule population variance estimate. This allowed correct standard error estimates to be used to compare dissolution in different media using planned linear contrasts. In vitro tests were performed using a standard USP basket apparatus (Vankel Inc., Cary, NC), and the analysis used the restricted/residual maximum likelihood method (JMP software) to partition the variance due to media (pH 1.2 and 6.8, +SDS, water alone and at pH 1.2 with pepsin), time (repeated measure) and capsule (random effect). 158, 183 in JMP, 17677, 177f, 178f in R, 17071, 170f linear models, use of term, 92 linear regression, definition of, 1 linear regression analysis. We have developed an analysis of variance model to analyze the overall dissolution profile obtained from the various media. Multiple regression: scatterplot matrices, correlations, using Fit Model for regressions, creating quadratic and product terms. Due to the large number of dissolution media available for solid dosage forms, a statistical method to choose the appropriate medium is critical for testing solid dosage forms. A powerful statistical method was designed using JMP software to detect factors contributing to differences in the dissolution process of an antiviral drug delivered in an oral dosage form. Multiple linear regression is used to estimate the relationship between two or more independent variables and one dependent variable.You can use multiple linear regression when you want to know.
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